Engineered T cells can serve as organ-specific delivery service

Drug design, drug delivery & technologies

Researchers from the University of California San Francisco (UCSF) have successfully replicated the design of regulatory T cells, achieving local targeted immune suppression and protection from CAR T-cell cytotoxicity. Many of the treatments used so far in the context of inflammatory and autoimmune disorders lead to systemic immunosuppression. In this sense, limiting immunosuppression locally to targeted tissues may help overcome systemic toxicity.

BioWorld BioWorld Science Science Drug design, drug delivery and technologies CAR T Cancer Neurology/psychiatric

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