The process by which fungi synthesize some of their most potent compounds has remained unclear for many years. This is especially true of cyclopentachromone, a key building block in fungal…
The anesthetic ketamine could be a game changer for treating severe depression, but there are still many questions about how the drug works, including how it affects the brain’s cells…
Staphylococcus aureus (S. aureus; SA/Sa) is a major cause of skin and soft tissue infections that can sometimes lead to sepsis and toxic shock syndrome. And while many S. aureus…
Drug discovery and novel disease treatments are major areas of research, with constant innovation. Delivering these drugs and treatments completely and precisely has been a major hurdle that researchers continue…
LAB eN², which aims to nurture early research from academic institutions into novel therapeutics, has selected its first three projects to move forward in the program from Boston University, Harvard…
When Milenko Cicmil, PhD, first heard about the technology underlying Tasca Therapeutics, a newly-minted small molecular inhibitor company, he was intrigued. The privately-held company, which launched this week with a…
The results of a preclinical study by lymphoma researchers at Weill Cornell Medicine suggest that an emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of…
Charles River Laboratories launched the Charles River Incubator Program (CIP), specializing in supporting early-stage biotech companies in the discovery, development, and phase-appropriate manufacturing of advanced therapies. “The Charles River Incubator…
Parkinson’s disease is characterized by the loss of dopamine-producing neurons. The current treatment is oral levodopa, which is taken up by brain neurons and converted to dopamine. But levodopa eventually…
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis in humans. The findings from…
