Multiple Factors Influence Host Cell Protein Levels
The production of many therapies based on monoclonal antibodies relies on Chinese Hamster Ovary (CHO) cells. Unfortunately, these cells also make host cell proteins (HCPs), which can make a drug…
Bioprocessing
From Byway to Royal Road
Biomanufacturing might appear to be centered around the cell line, which does enjoy a certain pride of place, ensconced as it is in the bioreactor, where conditions are carefully monitored…
Optimizing TFF for mRNA Filtration
As steadily increasing numbers of mRNA vaccines and therapeutics advance through clinical trials and commercialization, the biopharmaceutical industry is pressed to find ways to make their production increasingly cost-effective. But,…
Engineered Cell Membranes Enhance Industrial Bacteria’s Capabilities
Bacteria are a cornerstone of the pharmaceutical and chemical industries, helping produce everything from drugs and beer to biodiesel and fertilizer. The pharmaceutical industry, in particular, relies heavily on bacteria…
Panning the Golden Batch
Like an Olympian combining many precise steps on the journey to a gold medal, a bioprocessor develops a plan that turns substances from living cells into a therapy that raises…
Addressing the Puzzle of Bispecific Antibody Manufacturing
A custom antibody manufacturer is testing the best combination of molecular parts for bispecific manufacturing. According to Stefan Schmidt, PhD, CEO of Evitria, the company offers to test in parallel…
Bringing Advanced Research to Laboratories Worldwide
Sponsored content brought to you by Deploying advanced research environments is complex, hence the need for collaboration. SmartLabs reduces the financial and operational risks for life science innovators – no…
Cambrex Inks Deal with Lilly to Support Biotech Collaborator Manufacturing
Cambrex, a CDMO, signed an agreement with Eli Lilly to deliver accelerated access to clinical development capabilities for Lilly’s biotech collaborators. The company will partner with Lilly Catalyze360-ExploR&D, Lilly’s early…
Amgen Raises NC Investment to $1.5B with Plans for Second Plant
Amgen said today it will raise its biomanufacturing investment in Holly Springs, NC, to $1.5 billion, by establishing a second drug substance manufacturing plant there—thanks in part to nearly $5…
Machine Learning Promises to Increase Cell Culture Productivity
Machine learning can help improve drug production from cell culture by fine-tuning and quantifying cell culture media experiments. That’s the view of Bei-Wen Ying, PhD, a researcher from the University…